In Máfia Submundo, players are divided into two rival mafia families battling for control of a crime-ridden city, while police officers infiltrate to save the population. Each player receives a secret role card determining their faction and special abilities. During the game, players use their cards strategically to eliminate opponents, protect allies, and discover who is friend or foe. Bluffing and deduction are essential as players must figure out the identities of others while keeping their own allegiance hidden. The game progresses through rounds of card play and elimination until one faction achieves victory by eliminating all opponents or fulfilling their faction's win condition.